LipidMatch for Ion Mobility!
The first iteration of LipidMatch (IM) provides interactive visualizations combining mass spectrometric evidence (CCS, drift time, retention time, and accurate mass) to discern lipid homologous series and structures from non-targeted datasets. Simply upload your feature table (for example after using Agilent Mass Profiler), the CCS libraries, and homologous series file, select your parameters and run. LipidMatch IM does CCS matching across 1,517+ lipid entries contained in the CCS library (thank you Sheher, Agilent Technologies, and Katrina Leaptrot et. al. John A McLean's lab) ! Results can be opened in LipidMatch IM Visualizer and visualizations include normalized mass defect plots, retention time versus accurate mass plots, CCS/drift time versus accurate mass plots, 3D plots including retention time, m/z, and drift time, and tables of annotations and metadata. All graphs and tables are interactive and have cross-filtering such that when a user selects a feature or homologous series, all other visuals highlight the feature or series of interest. Check out our datasets page for examples of our interactive datasets generated which can be shared online!
Free software is great! But integrating and developing an entire lipidomics workflow which best uses your resources and team's expertise is not easy. How can you best make use of the technologies available and comprehensively and accurately report lipid values in your lab or to your customers? Contact us to speak to an expert and see if we have the training or services to take your research to the next level.